This exploratory research investigated the relationship between U.S. medical tourists’ personal values and their expectations and perceptions of the service quality of healthcare facilities located outside the U.S. Based on a sample of U.S. consumers, who had traveled abroad for medical care, stepwise regression results indicated that personal values, in particular self-fulfillment, warm relationship with others, sense of accomplishment, security, self-respect, and excitement, significantly predicted U.S. medical tourists’ expectations and perceptions of the service quality of foreign healthcare facilities. The study establishes a foundation for future research on the role of personal values in medical tourists’ evaluation of service quality in the rapidly growing medical tourism industry