Tourism zoning regulations represent an essential governance tool for controlling spatial development, protecting natural and cultural resources, managing visitor flows, and enhancing destination sustainability. This research evaluates the effectiveness of tourism zoning regulations by analyzing global case studies, reviewing zoning frameworks, and examining quantitative and qualitative evidence from 18 tourism regions across Asia, Europe, and Latin America. Findings reveal that zoning can significantly improve environmental conservation, reduce overcrowding, and support balanced regional development when implemented with strong enforcement, community involvement, and integrated planning. However, weaknesses arise from political interference, inconsistent monitoring, and inadequate coordination among stakeholders. The study proposes a multi-layered zoning effectiveness model to guide policymakers and planners